This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1921 Excerpt: ...in the liver and kidneys. Sections of the tongue show desquamation of the epithelium, especially from the surface of the fungiform papillae; the invasion of the epithelial cells by yeast fungi which has been shown by Kohlbriigge as well as by the Editor to take place is possibly a terminal infection. Lesions of the alimentary tract.--The principal and characteristic lesions are found in the alimentary tract. The bowel is thinned to such an extent as to be almost diaphanous. The serous coat is generally healthy, the muscular coat atrophied. The submucosa in places has undergone hypertrophic fibrous changes; and the mucous membrane from mouth to anus, either in patches or universally, is superficially eroded and interstitially atrophied. The internal surface of the bowel is coated with a thick layer of grey, tenacious mucus containing numerous yeast cells and branching mycelium, which conceals patches of congestion, of erosion, or even of ulceration, besides such evidences of similar antecedent disease as pigmented areas and thinscarred, cicatricial patches. The villi and glands are eroded, and in many places completely destroyed. Here and there minute spherical indurations, about the size of a pin's head and surrounded by a dark pigmented or congested areola, can be felt in the mucous membrane. On cutting into these, one finds them to be minute cyst-like dilatations of the follicles filled with a gummy, muco-purulent material. Sections of the diseased bowel show under the microscope corresponding changes, such as varying degrees of erosion or ulceration of the surface of the mucous membrane; degeneration of villi, glands, and follicles; the small raucous cysts referred to; sometimes small abscesses; and, also, infiltration by leucocytes of the basement membr...