This text provides the reader with a general comparison of the pandemic of influenza's effect in cities across the Western world: Frankfort, Marseille, Paris, Manchester, Atlanta, Chicago, San Diego, Guatemala City, and Rio de Janeiro. The work was done by scholars with expertize in the history of the area under consideration. They provide a brief description of the city's importance; statistical data on mortality and morbidity; an examination of the public health response; the pandemic's impact on everyday life; and the economic effect of the pandemic.