Eighteen-year-old Anna is still learning how to live in the world outside Advocate Hospital where she spent months there as a psychiatric patient. As her high school friends and boyfriend Murph head off to college, Anna still struggles to overcome the wounds of her past while navigating the challenges of the future. Anna wants to confide in Bridgett and Frances, the youngest and oldest of her siblings, but her family's reticent past, despite their efforts to change, stops her. Meanwhile, as Anna's friends of the fifth floor are released, they go on with their interrupted lives, and each is tested differently on the lessons they learned together.Nine years later, everyone receives a mailed letter from Jonny Love, a friend who Anna hasn't seen or heard from since her days on the fifth floor.