"Hell is Empty and All the Devils Are Here" is the story of Chad Strickland, his family and friends as they try to survive the onslaught of a virulent plague. The setting is in the near future in Central Washington. Chad and Mary Strickland, along with their neighbors, Dave Tippet and Heather Tunney band together to protect their children and their way of life. Along the way, Chris Vaughn and Amber Hoskins join their group as they are hounded out of their homes and forced to go on the road to escape a gang of infected bikers led by Special Agent Macklin who is in turn part of a bigger plot to over throw the US Government and take control.